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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG2
All Species:
6.67
Human Site:
S1246
Identified Species:
18.33
UniProt:
Q9H7P9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H7P9
NP_073746.2
1386
147915
S1246
K
P
G
G
S
L
A
S
H
V
A
R
L
E
S
Chimpanzee
Pan troglodytes
XP_001135904
1385
155562
R1253
Q
K
V
V
V
V
N
R
N
L
P
L
N
A
Q
Rhesus Macaque
Macaca mulatta
XP_001086919
1534
162840
S1393
N
P
G
G
S
L
A
S
H
V
A
R
L
E
S
Dog
Lupus familis
XP_541623
1488
157673
G1324
Q
S
L
A
R
R
Q
G
P
G
G
D
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAU7
1340
143358
S1221
L
T
P
P
H
S
P
S
L
S
T
R
Q
L
L
Rat
Rattus norvegicus
NP_001128444
1344
144083
L1216
R
V
A
T
S
E
S
L
D
L
T
P
P
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506571
1331
147843
G1208
R
S
R
S
V
P
N
G
M
M
E
P
A
Q
S
Chicken
Gallus gallus
XP_419671
1405
159118
Q1281
R
P
S
P
L
T
A
Q
M
A
T
Q
N
Y
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694345
1625
179545
S1397
P
T
P
T
G
S
S
S
Y
S
A
N
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
85.9
73.5
N.A.
70.4
71.7
N.A.
26.3
25
N.A.
28.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.4
87
77.2
N.A.
76.3
77.8
N.A.
39.6
40.2
N.A.
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
0
N.A.
13.3
13.3
N.A.
6.6
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
13.3
N.A.
13.3
33.3
N.A.
26.6
26.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
34
0
0
12
34
0
23
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
0
0
12
0
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
23
23
12
0
0
23
0
12
12
0
0
0
0
% G
% His:
0
0
0
0
12
0
0
0
23
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
12
0
12
23
0
12
12
23
0
12
23
12
12
% L
% Met:
0
0
0
0
0
0
0
0
23
12
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
23
0
12
0
0
12
23
0
0
% N
% Pro:
12
34
23
23
0
12
12
0
12
0
12
23
12
12
0
% P
% Gln:
23
0
0
0
0
0
12
12
0
0
0
12
12
23
12
% Q
% Arg:
34
0
12
0
12
12
0
12
0
0
0
34
0
0
0
% R
% Ser:
0
23
12
12
34
23
23
45
0
23
0
0
12
0
56
% S
% Thr:
0
23
0
23
0
12
0
0
0
0
34
0
0
0
0
% T
% Val:
0
12
12
12
23
12
0
0
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _